张梅教授
张梅,博士,教授,博士生导师,必赢唯一官方网站药学院中药化学系教师,四川省学术和技术带头人后备人选,四川省精品课程—《中药制剂分析》负责人。现任世界中医药学会联合会道地药材专委会常务理事,中华中医药学会中药分析分会常务委员,四川省分析测试学会色谱学委员会副主任委员。一直从事中药物质基础及中药质量控制与评价等方面的教学及科研工作,作为课题负责人及主研人员承担了国家自然科学基金及部省局级科研项目近40项,获得授权发明专利5项,作为主持人及第二主研获得四川省和成都市科技进步三等奖共3项。围绕以上研究工作在Natural Product Reports、Sensors and Actuators B: Chemical、Food Chemistry (中科院1区)、Journal of Ethnopharmacology、Microchemical Journal.、Biomedicine & Pharmacotherapy(中科院2区)等相关杂志及学术会议上公开发表及交流论文150余篇。作为主编、副主编及编委参与编写《当代药用植物典》系列专著及国家“十四·五”、“十三·五”、“十二·五”、“十一·五”、“十·五”等规划教材及教参20余部。
个人联系方式
zhangmei63@cdutcm.edu.cn
研究领域
研究领域涉及(1)中药物质基础及作用机制研究;(2)中药质量控制及评价方法研究;(3)中药分析新方法及新技术研究;(4)中药体内药物及其代谢产物分析等。
专利与奖励
专利(不超过10项):
获得授权发明专利5项
奖励(不超过10项):
作为课题负责人及主研人员承担了国家自然科学基金及部省局级科研项目近40项,作为主持人及第二主研获得四川省和成都市科技进步三等奖共3项
出版信息
1.代表性论文(不超过10项):
(1) Jia Wang, Fangyong Wei, Yu Wang, Qingze Liu, Runxi He, Yuxia Huang, Kuang Wei, Xuejun Xie*, Mei Zhang*. Exploring the quality markers and mechanism of Bushen Huoxue Prescription in prevention and treatment of diabetic retinopathy based on Chinmedomics strategy. Journal of Ethnopharmacology. DOI: 10.1016/j.jep.2022.116131
(2) Yuxia Huang, Jia Wang, Yu Wang, Wei Kuang, Mengjun Xie*, Mei Zhang*.Pharmacological mechanism and clinical study of Qiming granules in treating diabetic retinopathy based on network pharmacology and literature review. Journal of Ethnopharmacology. DOI: 10.1016/j.jep.2022.115861
(3) Haiyan Yang, Kejun Li, Yanping Wang, Xin Yuan*, Mei Zhang*. A label-free strategy for H2O2 assay by chemical vapor generation-atomic fluorescence spectrometry. Microchemical Journal. DOI: 10.1016/j.microc.2022.107965
(4) Liangli Li, Maohua Yang, Mei Zhang*, Mingyan Jia*. Inkjet-printed colorimetric sensor array for the rapid identifcation of adulterated Fritillariae cirrhosae bulbus. Sensors & Actuators: B. Chemical. DOI: 10.1016/j.snb.2022.132210
(5) Lulin Peng, Maohua Yang, Mei Zhang*, Mingyan Jia*. A ratiometric fluorescent sensor based on carbon dots for rapid determination of bisulfte in sugar. Food Chemistry. DOI: 10.1016/j.foodchem.2022.133265.
(6) Yueting Yu, Ziyu Zhu, Mengjun Xie, Liping Deng, Xuejun Xie*, Mei Zhang*. Investigation on the Q-markers of Bushen Huoxue Prescriptions for DR treatment based on chemometric methods and spectrum-effect relationship. Journal of Ethnopharmacology. DOI: 10.1016/j.jep.2021.114800
(7) Chen Yang, Lan Lu, Li Liao, Bin Zhang, Min Zeng, Kun Zou, Xia Liu, Mei Zhang*. Establishment of GC–MS method for the determination of Pseudomonas aeruginosa biofilm and its application in metabolite enrichment analysis. Journal of Chromatography B. DOI: 10.1016/j.jchromb. 2021.122839
(8) Kejun Li, Haiyan Yang, Xin Yuan*, Mei Zhang*. A novel and indirect method for L-cysteine detection in traditional Chinese medicines by chemical vapor generation-atomic fluorescence spectrometry. Microchemical Journal. DOI: 10.1016/j.microc.2021.106891.
(9) Miao Zeng, Longkai Qi, Yinrui Guo, Xiangxiang Zhu, Xiaocui Tang, Tianqiao Yong, Yizhen Xie, Qingping Wu, Mei Zhang*and Diling Chen*.Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice. Frontiers in Aging Neuroscience. DOI: 10.3389/fnagi.2021.628860
(10) Mengjun Xie, Yueting Yu, Ziyu Zhu, Liping Deng, Bo Ren*, Mei Zhang*. Simultaneous determination of six main components in BushenHuoxue prescription by HPLC-CAD. Journal of Pharmaceutical and Biomedical Analysis. DOI: 10.1016/j.jpba.2021.114087
2.代表性著作、教材(不超过10项):
作为主编、副主编及编委参与编写《当代药用植物典》系列专著及国家“十四·五”、“十三·五”、“十二·五”、“十一·五”、“十·五”等规划教材及教参20余部。
科研活动
承担的课题(不超过10项):
(1)国家自然科学基金面上项目:基于“体内谱效关联-网络靶点重构”研究补肾活血方防治早期糖尿病视网膜水肿效应物质基础及作用机制(82174273),2022/01- 2025/12,55万,负责人
(2)国家自然科学基金面上项目,基于“活性成分群-细胞效应表达” 研究补肾活血方配伍多点调控HIF-1/VEGF信号途径防治DR作用机制(81774202),2018/01-2021/12,55万,负责人
(3)四川省应用基础研究重点项目:基于多维谱效关系及体内动态效应研究补肾活血方防治DR药效物质基础(2017JY0013) 2017/01-2019/12,30万,负责人
(4)必赢唯一官方网站一流学科项目:中药有效有害成分快速分析方法研究(CXTD2018010),2018/01-2022/12,100万,负责人