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博士研究生导师

石三军

个人简介

石三军,教授、博士生导师。哈佛大学留学归国,入选四川省中医药管理局学术和技术带头人和四川省学术和技术带头人后备人选、四川省高层次人才引进计划、四川省特聘专家、四川省杰青人才、省级创新创业优秀指导教师等;致力于传统脂质材料、新型安全材料在核酸蛋白药物及中药活性分子递释上的应用基础研究,其中开发的超分子复合物技术包载核酸药物被多位美韩科学家评价为首次研究报道。相关成果以第一或通讯作者身份在Angew Chem Int Edit, Nano Today, J Control Release, Acta Pharmaceutica Sinica B等顶级杂志上发表SCI论文多篇,参编《药剂学》和英文专著各1项,授权专利1项;先后主持了国家科技重大专项(726万)、国家自然科学基金等项目8项,累计经费1000余万元;成果先后获得重庆市科技进步二等奖、四川省科学技术进步三等奖、重庆市科协自然科学优秀学术论文,以及Int J Biol Macromol评审“杰出贡献奖”等奖项;指导学生获得“互联网+”创新创业竞赛国家级奖励2项、“挑战杯”大学生创业大赛国家级铜奖及“创青春”中国青年创新创业大赛铜奖,以及部省级创新创业奖励10余项;同时担任了本学科著名SCI期刊Curr Pharm Design客座主编、Asian J Pharm SciJournal of Pharmaceutical Analysis (IF=14)青年编委、Frontiers in PharmacologyFrontiers in Oncology客座编辑、SmartMat青年编委、《现代肿瘤医学》编委,并任世中联肿瘤精准医学专委会常务理事、中华中医药学会中成药分会委员、省科青联理事、省药学会药剂专委会委员等职务。



个人联系方式

shisanjuns@163.com


研究领域

致力于传统脂质材料、新型安全材料在核酸蛋白药物及中药活性分子递释上的应用基础研究,其中开发的超分子复合物技术包载核酸药物被多位美韩科学家评价为首次研究报道。


专利与奖励

奖励:

1)重庆市科技进步二等奖

2)四川省科学技术进步三等奖

3)重庆市科协自然科学优秀学术论文

4Int J Biol Macromol评审“杰出贡献奖”等奖项

5)指导学生获得“互联网+”创新创业竞赛国家级奖励2

6)“挑战杯”大学生创业大赛国家级铜奖及“创青春”中国青年创新创业大赛铜奖

7)以及部省级创新创业奖励10余项


出版信息

代表性论文:

(1)Dandan Mi, Jiaojiao Li, Rujing Wang, Yuke Li, Lan Zou, Chen Sun, Shenao Yan, Huan Yang, Mengnan Zhao*, Sanjun Shi*. Postsurgical wound management and prevention of triple-negative breast cancer recurrence with a pryoptosis-inducing, photopolymerizable hydrogel. Journal of Controlled Release, 2023; 356: 205-218. (IF=10.8)

(2)Ruijing Wang, Lan Zou, Zhiwen Yi, Zhen Zhang, Mengnan Zhao, Sanjun Shi*. PLGA nanoparticles loaded with curcumin produced luminescence for cell bioimaging. International Journal of Pharmaceutics. 2023; 122944. (IF=5.8)

(3)Mengnan Zhao, Rujing Wang, Kunmeng Yang, Yuhong Jiang*, Yachen Peng, Yuke Li, Zhen Zhang, Jianxun Ding*, Sanjun Shi*. Nucleic acid nanoassembly-enhanced RNA therapeutics and diagnosis. Acta Pharmaceutica Sinica B, 2023; 13: 916-941. (IF=14.5)

(4)Yao Chen, Jiru Yang, Yi Zuo, Chaozheng Zhang, Yiru Pu, QingRen, XiaoLi, Yunqian Huang, Hui Huang, HuanYang, Ouyan You, Xila Xia, Aiping Lu, Sanjun Shi*, Yun Deng*, Jun Lu*. Voacamine is a novel inhibitor of EGFR exerting oncogenic activity against colorectal cancer through the mitochondrial pathway. Pharmacological Research, 2022; 184: 106415. (IF=9.3)

(5)Yan Chen, Rui Zhang, Dandan Mi, Qiuju Wang, Tingwenli Huang, Xinwei Dong, Hongwei Zhang, Hongtao Xiao, Sanjun Shi*. SPK1/S1P axis confers gastrointestinal stromal tumors (GISTs) resistance of imatinib. Gastric Cancer, 2023; 26: 26-43. (IF=7.4)

(6)Mengnan Zhao, Dandan Mi, Bijan Emiliano Ferdows, Yuke Li, Rujing Wang, Jiaojiao Li, Dylan Patel, Sanjun Shi*, Wei Tao*. State-of-the-art nanotechnologies for the detection, recovery, analysis and elimination of blood-based biosources in cancer liquid biopsy. Nano Today, 2022; 42: 101361. (IF=17.4)

(7)Hanmei Li, Qi Tang, Yao Wang, Mao Li, Yannan Wang, Hong Zhu, Fang Geng, Di Wu, Lianxin Peng, Gang Zhao, Liang Zou, Sanjun Shi*. Injectable thermosensitive lipo-hydrogels loaded with ropivacaine for prolonging local anesthesia. International Journal of Pharmaceutics, 2021; 121291. (IF=5.8)

(8)Hong Wang, Yu Zheng, Qiang Sun, Zhen Zhang, Mengnan Zhao, Cheng Peng*, Sanjun Shi*. Ginsenosides emerging as both bifunctional drugs and nanocarriers for enhanced antitumor therapies. Journal of Nanobiotechnology, 2021; 19: 322. (IF=10.2)

(9)Xili Lu#, Sanjun Shi#, Hanmei Li, Ethan Gerhard, Zhihui Lu, Xinyu Tan, Wenliang Li, Kevin M.Rahn, Denghui Xie, Guodong Xu, Fang Zou, Xiaochun Bai, Jinshan Guo, Jian Yang. Magnesium oxide-crosslinked low-swelling citrate-based mussel-inspired tissue adhesives. Biomaterials, 2020; 232: 119719. (IF=14)

(10)Lili Wei, Chenyuan Wang, Xianjue Chen, Bing Yang, Kun Shi, Leah R. Benington, Lee Yong Lim, Sanjun Shi*, Jingxin Mo*. Dual-responsive, methotrexate-loaded, ascorbic acid-derived micelles inhibit NF-κB signaling to exert anti-tumor and anti-metastasis effects in an orthotopic mouse model of human choriocarcinoma. Theranostics, 2019; 9(15): 4354-4374. (IF=12.4)


科研活动

承担的课题

参编《药剂学》和英文专著各1项,授权专利1项;先后主持了国家科技重大专项(726万)、国家自然科学基金等项目8项,累计经费1000余万元


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