王勇
教授,博士研究生导师,必赢唯一官方网站海外引进人才。担任中国研究型医院学会中西医结合新药创制专业委员会委员,中国民族医药学会药理与毒理学会理事,四川国际医学交流促进会青年委员,中国中西医结合学会第八届活血化瘀专业委员会中药药理专家委员会等。承担本科生《人体解剖学》《组织学与胚胎学》《科研思维与方法》理论教学与实验教学。已经培养硕士研究生5名,其中继续攻读博士学位2名,医院就业1名,高校老师2名。
个人联系方式
yongwang1008@hotmail.com
研究领域
(1)心血管发育及心血管疾病发病机理;(2)中医药对心血管疾病的防治作用及机理。
招生信息
招生专业:中西医结合基础
出版信息
代表性论文:
(1)Jin Z, Guo Q, Wang Z, Wu X, Hu W, Li J, Li H, Zhu S, Zhang H, Chen Z, Xu H, Shi L, Yang L, Wang Y. Andrographolide suppresses hypoxia-induced embryonic hyaloid vascular system development through HIF-1a/VEGFR2 signaling pathway. Front Cardiovasc Med. 2023 Feb 8;10:1090938. doi: 10.3389/fcvm.2023.1090938. PMID: 36844722; PMCID: PMC9944699.
(2)Wang Z, Wu X, Li J, Guo Q, Jin Z, Li H, Liang B, Hu W, Xu H, Shi L, Yang L, Wang Y. Potassium Dehydroandrograpolide Succinate Targets NRP1 Mediated VEGFR2/VE-Cadherin Signaling Pathway to Promote Endothelial Barrier Repair. Int J Mol Sci. 2023 Feb 4;24(4):3096. doi: 10.3390/ijms24043096. PMID: 36834519; PMCID: PMC9964616.
(3)Wangming Hu, Wu Xiao, Zhong Jin, Zheng Wang, Qiru Guo, Zixian Chen, Song Zhu, Haidi Zhang, Huo Jian, Lingling Zhang, Xin Zhou, Lan Yang, Huan Xu, Liangqing Shi, Yong Wang. Andrographolide promotes interaction between endothelin-dependent EDNR1/EDNRB and Myocardin-SRF to regulate pathological vascular remodeling. Front Cardiovasc Med. 2022 Jan 20;8:783872. doi: 10.3389/fcvm.2021.783872. PMID: 35127859; PMCID: PMC8810813. (通讯作者;影响因子:5.846)
(4)Yong Wang, Yiming Xu, Siyuan Yan, Kaixiang Cao, Xianqiu Zeng, Yaqi Zhou, Zhiping Liu, Qiuhua Yang, Yue Pan, Xiaoling Wang, Detlev Boison, Yunchao Su, Xuejun Jiang, Vijay S. Patel, David Fulton, Neal L. Weintraub, and Yuqing Huo. Adenosine kinase is critical for neointima formation after vascular injury by inducing aberrant DNA hypermethylation. Cardiovasc Res. 2021 Jan 21;117(2):561-575. doi: 10.1093/cvr/cvaa040. PMID: 32065618; PMCID: PMC7820850.(高被引论文)
(5)Yiming Xu, Yong Wang, Siyuan Yan, Qiuhua Yang, Yaqi Zhou, Xianqiu Zeng, Zhiping Liu, Xiaofei An, Haroldo A.Toque, Zheng Dong, Xuejun Jiang, David J.Fulton, Neal L.Weintraub, Qinkai Li, Zsolt Bagi, Mei Hong, Detlev Boison, Chaodong Wu, Yuqing Huo. Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation. Nat Commun. 2017 Oct 16;8(1):943. doi: 10.1038/s41467-017-00986-7. PMID: 29038540; PMCID: PMC5643397.
(6)Yong Wang, Guoqing Hu, Fang Liu, Xiaobo Wang, Mingfu Wu, John J. Schwarz, Jiliang Zhou. Deletion of YAP specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development. Circ Res. 2014 Mar 14;114(6):957-65. doi: 10.1161/CIRCRESAHA.114.303411. Epub 2014 Jan 29. PMID: 24478334; PMCID: PMC4049286. (杂志封面文章)
科研活动
代表性课题:
(1)国家自然科学基金委员会,面上项目,平滑肌细胞腺苷激酶对血管重塑的作用及机理
(2)国家自然科学基金委员会,应急管理项目,L-NAME-NOS-NO信号通路抑制糖酵解途径而调节大鼠胚胎发育后期后肢发育的作用及机理研究
(3)四川省科学技术厅青年科技创新团队项目,ANP对病理性血管重塑及肌肉损伤后再生的作用机理研究
(4)必赢唯一官方网站“杏林学者”学科人才科研提升计划拔尖人才项目,腺苷激酶在血管重塑的作用及机理